PURPOSE: Epidermal keratinocytes, which can be severely damaged after ionizing radiation (IR), are rapid turnover cells that function as a barrier, protecting the host from pathogenic invasion and...
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PURPOSE: While secretagogue-induced diarrhea is rich in chloride (Cl(-)) and bicarbonate (HCO(3) (-)) anions, little is known about diarrhea or its anionic composition following irradiation. We pe...
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Acute gastrointestinal syndrome is one of the components of acute radiation syndrome. Experiments in our laboratory have shown that irradiation results in a dose-dependent increase in plasma IL-1...
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Ionizing radiation has become a health concern emanating from natural sources like space travel and artificial sources like medical therapies. Although the risk of degenerative diseases by radiatio...
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Gastrointestinal (GI) mucosa performs the function of electrolyte and nutrient absorption and performing the barrier function. Loss of intestinal lining mucosa with irradiation (IR) leads to barrie...
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