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Research

Based on SEER database, gastroenteropancreatic neuroendocrine tumor incidence has increased 6 fold from 1 in 100,000 cases to about 6 in 100,000 cases over past 3 decades. North American Neuroendoc...

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Constantine Mantz, MD, 21st Century Oncology, Fort Myers, FL Institution: 21st Century Oncology (complete) Title: Pragmatic test of amino-acid mixture/enterade® for Gastrointestinal Toxicity in...

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Rotavirus causes severe diarrhea in small children and is typically treated using glucose-containing oral rehydration solutions; however, glucose may have a detrimental impact on these patients, be...

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Entrinsic Health Solutions, Inc., an innovative health sciences company dedicated to the development and commercialization of amino acid-based medical foods to address critical digestive health, nu...

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Entrinsic Health Solutions, Inc., an innovative health sciences company dedicated to the development and commercialization of amino acid-based medical foods to address critical digestive health, nu...

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When patients get treated for cancer, radiation therapy administered to shrink tumors also affects healthy cells in the gastrointestinal tract and causes difficult side effects. Now, a group of Uni...

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This research study is evaluating Enterade, a supplement, as a possible treatment for the side effects caused by Stem Cell Transplant. The following interventions will be involved in this study:...

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Publications

 Aman Chauhan, MBBS, University of Kentucky explains enterade® Amino Acid Based Rehydration Solution | 70% of Patients Had Benefit in Diarrhea Reduction at Annual Meeting 2018 Click on the link ...

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Entrinsic Health Solutions in partnership with the Markey Cancer Center, today announced clinical data from a pilot study examining the anti-diarrheal efficacy of enterade®, an amino acid based sol...

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Background: Based on SEER database, gastroenteropancreatic neuroendocrine tumor (GEPNET) incidence has increased 6-fold from 1 in 100,000 cases to about 6 in 100,000 cases over past 3 decades. Nor...

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The efficacy of different commercial beverage compositions for meeting oral rehydration therapy (ORT) goals in the treatment of acute dehydration in healthy humans has not been systematically teste...

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Short chain fatty acids, particularly butyrate, stimulate electroneutral NaCl absorption from the colon. Their effect in colonic epithelia lacking basal electroneutral NaCl absorption is unknown. B...

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Electrolyte and nutrient absorption occur in villous epithelial cells. Radiation often results in reduced electrolyte and nutrient absorption, which leads to gastrointestinal toxicity. Therefore, t...

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The sodium-coupled glucose transporter-1 (SGLT1)-based oral rehydration solution (ORS) used in the management of acute diarrhea does not substantially reduce stool output, despite the fact that glu...

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PURPOSE: Epidermal keratinocytes, which can be severely damaged after ionizing radiation (IR), are rapid turnover cells that function as a barrier, protecting the host from pathogenic invasion and...

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PURPOSE: While secretagogue-induced diarrhea is rich in chloride (Cl(-)) and bicarbonate (HCO(3) (-)) anions, little is known about diarrhea or its anionic composition following irradiation. We pe...

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Acute gastrointestinal syndrome is one of the components of acute radiation syndrome. Experiments in our laboratory have shown that irradiation results in a dose-dependent increase in plasma IL-1...

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Ionizing radiation has become a health concern emanating from natural sources like space travel and artificial sources like medical therapies. Although the risk of degenerative diseases by radiatio...

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Gastrointestinal (GI) mucosa performs the function of electrolyte and nutrient absorption and performing the barrier function. Loss of intestinal lining mucosa with irradiation (IR) leads to barrie...

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